自閉症スペクトラム障害について 備忘録など










 In recent years the use of psychostimulants for cognitive enhancement in healthy individuals with no psychiatric disorders has been on the rise.
However, it is still unclear whether psychostimulants improve certain cognitive functions at the cost of others, and how these psychostimulants interact
with individual personality differences. In the current study, we investigated whether the effect of one common stimulant, methylphenidate (MPH), on
creativity is associated with novelty seeking. Thirty-six healthy adults, without attention-deficit hyperactivity disorder (ADHD) symptomology, were
assigned randomly in a double-blind fashion to receive MPH or placebo. We found that the effect of MPH on creativity was dependent on novelty-
seeking (NS) personality characteristics of the participants. MPH increased creativity in individuals with lower NS, while it reduced creativity levels in
individuals with high NS. These findings highlight the role of the dopaminergic system in creativity, and indicate that among healthy individuals NS
can be seen as a predictor of the effect of MPH on creativity.



Novelty-seeking trait predicts the effect of methylphenidate on creativity

Hila Z Gvirts Naama Mayseless, Aviv Segev 
D Yael Lewis,Kfir Feffer, Yael Barnea, Yuval Bloch
and Simon G Shamay-Tsoory

Journal of psychopharmacology (Oxford, England). 2016